human PADI2 shRNA silencing Adenovirus

Name 
Ad-h-PADI2-shRNA
Cat No 
shADV-218114
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PADI2.

shADV-218114
Ad-h-PADI2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PADI2 (peptidyl arginine deiminase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PAD-H19; PAD2; PDI2
Description (Vector)
PADI2 encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. PADI2 exists in a cluster with four other paralogous genes.
Gene ID
11240
Gene Name (Vector)
peptidyl arginine deiminase 2
Gene Symbol
PADI2
HGNC ID
HGNC:18341
ORF Size (aa)
1314
ORF Size (bp)
1314 bp
RefSeq ID
NM_007365
RefSeq Synonyms
NM_007365, BC009701,
Species
human
UniGene ID
Hs.33455

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.