human P2RX4 shRNA silencing Adenovirus

Name
Ad-h-P2RX4-shRNA

Cat No
shADV-218045

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human P2RX4.

shADV-218045

Ad-h-P2RX4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human P2RX4 (purinergic receptor P2X 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

P2X4; P2X4R

Description (Vector)

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.

Gene ID

5025

Gene Name (Vector)

purinergic receptor P2X 4

Gene Symbol

P2RX4

HGNC ID

HGNC:8535

ORF Size (aa)

1167

RefSeq ID

NM_002560

RefSeq Synonyms

NM_002560, NM_001261398, NM_001261397, NM_001256796, BC033826,

Species

human

UniGene ID

Hs.321709

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.