human OTC shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human OTC.
shADV-217979
Ad-h-OTC-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human OTC (ornithine carbamoyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
OCTD
Description (Vector)
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Gene ID
5009
Gene Name (Vector)
ornithine carbamoyltransferase
Gene Symbol
OTC
HGNC ID
HGNC:8512
ORF Size (aa)
1065
RefSeq ID
NM_000531
RefSeq Synonyms
NM_000531, BC114496, BC107154, BC107153, BC074745,
Species
human
UniGene ID
Hs.117050
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.