human OPTC shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human OPTC.
shADV-217448
Ad-h-OPTC-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human OPTC (opticin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
OPT
Description (Vector)
Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).
Gene ID
26254
Gene Name (Vector)
opticin
Gene Symbol
OPTC
HGNC ID
HGNC:8158
ORF Size (aa)
999
ORF Size (bp)
999 bp
RefSeq ID
NM_014359
RefSeq Synonyms
NM_014359, BC074943, BC074942,
Species
human
UniGene ID
Hs.632468
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.