human OPN4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human OPN4.
shADV-217441
Ad-h-OPN4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human OPN4 (opsin 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MOP
Description (Vector)
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
94233
Gene Name (Vector)
opsin 4
Gene Symbol
OPN4
HGNC ID
HGNC:14449
ORF Size (aa)
1437
ORF Size (bp)
1437 bp
RefSeq ID
NM_033282
RefSeq Synonyms
NM_033282, NM_001030015, BC143688, BC113558,
Species
human
UniGene ID
Hs.283922
Recently Viewed Products
Ad-m-NNT-shRNA
Cat No: shADV-265898
AAV-m-2310022A10RIK-shRNA
Cat No: shAAV-250650
Ad-r-GSTM1-shRNA
Cat No: shADV-290451
AAV-h-NOC4L-shRNA
Cat No: shAAV-216852
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.