human OFD1 shRNA silencing Adenovirus

Name
Ad-h-OFD1-shRNA

Cat No
shADV-217372

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human OFD1.

shADV-217372

Ad-h-OFD1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human OFD1 (OFD1, centriole and centriolar satellite protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

71-7A; CXorf5; JBTS10; RP23; SGBS2

Description (Vector)

OFD1 is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. Alternatively spliced transcripts have been described for this gene but the biological validity of these transcripts has not been determined.

Gene ID

8481

Gene Name (Vector)

OFD1, centriole and centriolar satellite protein

Gene Symbol

OFD1

HGNC ID

HGNC:2567

ORF Size (aa)

2919

ORF Size (bp)

2919 bp

RefSeq ID

NM_003611

RefSeq Synonyms

NM_003611, NM_001330210, NM_001330209, BC096344,

Species

human

UniGene ID

Hs.6483

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.