human NYX shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NYX.
shADV-217303
Ad-h-NYX-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NYX (nyctalopin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CLRP; CSNB1; CSNB1A; CSNB4; NBM1
Description (Vector)
The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.
Gene ID
60506
Gene Name (Vector)
nyctalopin
Gene Symbol
NYX
HGNC ID
HGNC:8082
ORF Size (aa)
1446
ORF Size (bp)
1446 bp
RefSeq ID
NM_022567
RefSeq Synonyms
NM_022567, BC112242,
Species
human
UniGene ID
Hs.302019
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.