human NXT1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NXT1.
shADV-217297
Ad-h-NXT1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NXT1 (nuclear transport factor 2 like export factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MTR2; P15
Description (Vector)
NXT1 is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.
Gene ID
29107
Gene Name (Vector)
nuclear transport factor 2 like export factor 1
Gene Symbol
NXT1
HGNC ID
HGNC:15913
ORF Size (aa)
423
RefSeq ID
NM_013248
RefSeq Synonyms
NM_013248, BC003410, BC003029, BC002687, BC000759,
Species
human
UniGene ID
Hs.516933
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.