human NTRK1 shRNA silencing Adenovirus

Name 
Ad-h-NTRK1-shRNA
Cat No 
shADV-217164
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NTRK1.

shADV-217164
Ad-h-NTRK1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NTRK1 (neurotrophic receptor tyrosine kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
88
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA
Description (Vector)
NTRK1 encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Gene ID
4914
Gene Name (Vector)
neurotrophic receptor tyrosine kinase 1
Gene Symbol
NTRK1
HGNC ID
HGNC:8031
ORF Size (aa)
2373
ORF Size (bp)
2373 bp
RefSeq ID
NM_002529
RefSeq Synonyms
NM_002529, NM_001012331, NM_001007792, BC144239, BC136554,
Species
human
UniGene ID
Hs.406293

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.