human NRXN2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NRXN2.
shADV-217106
Ad-h-NRXN2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NRXN2 (neurexin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
NRXN2 encodes a member of the neurexin gene family. The products of these genes function as cell adhesion molecules and receptors in the vertebrate nervous system. These genes utilize two promoters. The majority of transcripts are produced from the upstream promoter and encode alpha-neurexin isoforms while a smaller number of transcripts are produced from the downstream promoter and encode beta-neuresin isoforms. The alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and have been shown to interact with neurexophilins. The beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. Alternative splicing and the use of alternative promoters may generate thousands of transcript variants (PMID: 12036300, PMID: 11944992).
Gene ID
9379
Gene Name (Vector)
neurexin 2
Gene Symbol
NRXN2
HGNC ID
HGNC:8009
ORF Size (aa)
4929
ORF Size (bp)
4929 bp
RefSeq ID
NM_015080
RefSeq Synonyms
NM_138734, NM_138732, NM_015080, BC150275,
Species
human
UniGene ID
Hs.372938
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.