human NRF1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NRF1.
shADV-217074
Ad-h-NRF1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NRF1 (nuclear respiratory factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALPHA-PAL
Description (Vector)
NRF1 encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.
Gene ID
4899
Gene Name (Vector)
nuclear respiratory factor 1
Gene Symbol
NRF1
HGNC ID
HGNC:7996
ORF Size (aa)
1569
ORF Size (bp)
1569 bp
RefSeq ID
NM_005011
RefSeq Synonyms
NM_005011, NM_001293164, NM_001293163, NM_001040110, BC016925,
Species
human
UniGene ID
Hs.654363
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.