human NOS1AP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NOS1AP.
shADV-216903
Ad-h-NOS1AP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NOS1AP (nitric oxide synthase 1 adaptor protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
6330408P19Rik; CAPON
Description (Vector)
NOS1AP encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
9722
Gene Name (Vector)
nitric oxide synthase 1 adaptor protein
Gene Symbol
NOS1AP
HGNC ID
HGNC:16859
ORF Size (aa)
1521
ORF Size (bp)
1521 bp
RefSeq ID
NM_014697
RefSeq Synonyms
NM_014697, NM_001164757, NM_001126060, BC118499, BC112295, BC111928,
Species
human
UniGene ID
Hs.655000
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.