human NOP56 shRNA silencing Adenovirus

Name 
Ad-h-NOP56-shRNA
Cat No 
shADV-216896
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NOP56.

shADV-216896
Ad-h-NOP56-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NOP56 (NOP56 ribonucleoprotein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NOL5A; NOP56 ribonucleoprotein homolog; nucleolar protein 56; Nucleolar protein 5A; nucleolar protein 5A (56kDa with KKE/D repeat); SCA36
Description (eCommerce)
Nucleolar protein 56 (NOP56) is a core component of the box C/D snoRNP complex. The snoRNP core complex is made up of NOP58, NOP56, and fibrillin and is involved in ribosome biogenesis.
Description (Vector)
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined.
Gene ID
10528
Gene Name (eCommerce)
NOP56 ribonucleoprotein
Gene Name (Vector)
NOP56 ribonucleoprotein
Gene Symbol
NOP56
HGNC ID
HGNC:15911
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1785
ORF Size (bp)
1785 bp
Protein Name (eCommerce)
Nucleolar protein 56
RefSeq ID
NM_006392
RefSeq Synonyms
NM_006392, BC104793, BC104791, BC004937,
Research Areas
Apoptosis,Neurobiology,Neurodegeneration,Protein Folding,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,neurobiology,genetics,transcription_translation
Species
human
Target Sentence
Nucleolar protein 56 (NOP56) is a core component of the box C/D snoRNP complex. The snoRNP core complex is made up of NOP58, NOP56, and fibrillin and is involved in ribosome biogenesis.
UniGene ID
Hs.376064
UniProt ID (eCommerce)
O00567

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.