human NOD1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NOD1.
shADV-216854
Ad-h-NOD1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NOD1 (nucleotide binding oligomerization domain containing 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CARD4; CLR7.1; NLRC1
Description (Vector)
NOD1 encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.
Gene ID
10392
Gene Name (Vector)
nucleotide binding oligomerization domain containing 1
Gene Symbol
NOD1
HGNC ID
HGNC:16390
ORF Size (aa)
2862
ORF Size (bp)
2862 bp
RefSeq ID
NM_006092
RefSeq Synonyms
NM_006092, BC040339,
Species
human
UniGene ID
Hs.405153
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.