human NME1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NME1.
shADV-216817
Ad-h-NME1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NME1 (NME/NM23 nucleoside diphosphate kinase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1
Description (Vector)
NME1 (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Gene ID
4830
Gene Name (Vector)
NME/NM23 nucleoside diphosphate kinase 1
Gene Symbol
NME1
HGNC ID
HGNC:7849
ORF Size (aa)
459
RefSeq ID
NM_000269
RefSeq Synonyms
NM_198175, NM_000269, BC018994, BC000293,
Species
human
UniGene ID
Hs.463456
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.