human NKX2-1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NKX2-1.
shADV-216761
Ad-h-NKX2-1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NKX2-1 (NK2 homeobox 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BCH; BHC; NK-2; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; TITF1; TTF-1; TTF1
Description (Vector)
NKX2-1 encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. NKX2-1 shares the symbol/alias 'TFF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.
Gene ID
7080
Gene Name (Vector)
NK2 homeobox 1
Gene Symbol
NKX2-1
HGNC ID
HGNC:11825
ORF Size (aa)
1116
ORF Size (bp)
1116 bp
RefSeq ID
NM_003317
RefSeq Synonyms
NM_003317, NM_001079668, BC006221,
Species
human
UniGene ID
Hs.94367
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.