human NKRF shRNA silencing Adenovirus

Name 
Ad-h-NKRF-shRNA
Cat No 
shADV-216757
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NKRF.

shADV-216757
Ad-h-NKRF-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NKRF (NFKB repressing factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ITBA4; NF-kappa-B-repressing factor; NFkB-repressing factor; NRF; Protein ITBA4; transcription factor NRF
Description (eCommerce)
NFkappaB repressing factor (NRF) is a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. NRF localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm [taken from NCBI Entrez Gene (Gene ID: 55922)].
Description (Vector)
NKRF encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants.
Gene ID
55922
Gene Name (eCommerce)
NFKB repressing factor
Gene Name (Vector)
NFKB repressing factor
Gene Symbol
NKRF
HGNC ID
HGNC:19374
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2073
ORF Size (bp)
2073 bp
Protein Name (eCommerce)
NF-kappa-B-repressing factor
RefSeq ID
NM_017544
RefSeq Synonyms
NM_017544, NM_001173488, NM_001173487, BC068514, BC047878, BC040379,
Research Areas
RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
NFkappaB repressing factor (NRF) is a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. NRF localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm [taken from NCBI Entrez Gene (Gene ID: 55922)].
UniGene ID
Hs.437084
UniProt ID (eCommerce)
O15226

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.