human NFE2L2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NFE2L2.
shADV-216638
Ad-h-NFE2L2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NFE2L2 (nuclear factor, erythroid 2 like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HEBP1; NRF2
Description (Vector)
NFE2L2 encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
4780
Gene Name (Vector)
nuclear factor, erythroid 2 like 2
Gene Symbol
NFE2L2
HGNC ID
HGNC:7782
ORF Size (aa)
1818
ORF Size (bp)
1818 bp
RefSeq ID
NM_006164
RefSeq Synonyms
NM_006164, NM_001313904, NM_001313903, NM_001313902, NM_001313901, NM_001313900, NM_001145413, NM_001145412, BC011558,
Species
human
UniGene ID
Hs.715540
Related Citations
- Regulation of vascular large-conductance calcium-activated potassium channels by Nrf2 signalling. Li Y, etc, (2017), Diabetes and Vascular Disease Research
- Role of Nrf2 Signaling in the Regulation of Vascular BK Channel Beta-1 Subunit Expression and BK Channel Function in High Fat Diet-Induced Diabetic Mice. Lu T, etc, (2017), Diabetes
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.