human NEIL3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NEIL3.
shADV-216566
Ad-h-NEIL3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NEIL3 (nei like DNA glycosylase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FGP2; FPG2; hFPG2; hNEI3; NEI3; ZGRF3
Description (Vector)
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 (PubMed 12509226)).(supplied by OMIM, Mar 2008)
Gene ID
55247
Gene Name (Vector)
nei like DNA glycosylase 3
Gene Symbol
NEIL3
HGNC ID
HGNC:24573
ORF Size (aa)
1818
ORF Size (bp)
1818 bp
RefSeq ID
NM_018248
RefSeq Synonyms
NM_018248, BC025954,
Species
human
UniGene ID
Hs.405467
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.