human NEIL2 shRNA silencing Adenovirus

Name 
Ad-h-NEIL2-shRNA
Cat No 
shADV-216564
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human NEIL2.

shADV-216564
Ad-h-NEIL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NEIL2 (nei like DNA glycosylase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NEH2; NEI2
Description (Vector)
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 (PubMed 12509226))(supplied by OMIM, Mar 2008)
Gene ID
252969
Gene Name (Vector)
nei like DNA glycosylase 2
Gene Symbol
NEIL2
HGNC ID
HGNC:18956
ORF Size (aa)
999
ORF Size (bp)
999 bp
RefSeq ID
NM_145043
RefSeq Synonyms
NM_145043, NM_001135748, NM_001135747, NM_001135746, BC013964, BC013952,
Species
human
UniGene ID
Hs.293818

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.