human NEBL shRNA silencing Adenovirus

Name 
Ad-h-NEBL-shRNA
Cat No 
shADV-216541
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human NEBL.

shADV-216541
Ad-h-NEBL-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NEBL (nebulette). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LASP2; LNEBL
Description (Vector)
NEBL encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants.
Gene ID
10529
Gene Name (Vector)
nebulette
Gene Symbol
NEBL
HGNC ID
HGNC:16932
ORF Size (aa)
3045
ORF Size (bp)
3045 bp
RefSeq ID
NM_006393
RefSeq Synonyms
NM_213569, NM_006393, NM_001173484, BC110453, BC110452,
Species
human
UniGene ID
Hs.5025

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.