human NDRG1 shRNA silencing Adenovirus

Name 
Ad-h-NDRG1-shRNA
Cat No 
shADV-216456
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NDRG1.

shADV-216456
Ad-h-NDRG1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NDRG1 (N-myc downstream regulated 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAP43; CMT4D; DRG-1; DRG1; GC4; HMSNL; NDR1; NMSL; PROXY1; RIT42; RTP; TARG1; TDD5
Description (Vector)
NDRG1 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
10397
Gene Name (Vector)
N-myc downstream regulated 1
Gene Symbol
NDRG1
HGNC ID
HGNC:7679
ORF Size (aa)
1185
ORF Size (bp)
1185 bp
RefSeq ID
NM_006096
RefSeq Synonyms
NM_006096, NM_001258433, NM_001258432, NM_001135242, BC006260, BC003175,
Species
human
UniGene ID
Hs.372914

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.