human NDP shRNA silencing Adenovirus

Name 
Ad-h-NDP-shRNA
Cat No 
shADV-216455
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human NDP.

shADV-216455
Ad-h-NDP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NDP (NDP, norrin cystine knot growth factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EVR2; FEVR; ND
Description (Vector)
NDP encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy.
Gene ID
4693
Gene Name (Vector)
NDP, norrin cystine knot growth factor
Gene Symbol
NDP
HGNC ID
HGNC:7678
ORF Size (aa)
402
RefSeq ID
NM_000266
RefSeq Synonyms
NM_000266, BC029901,
Species
human
UniGene ID
Hs.522615

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.