human NCRNA00153 shRNA silencing Adenovirus

Name 
Ad-h-NCRNA00153-shRNA
Cat No 
shADV-216437
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KIZ.

shADV-216437
Ad-h-NCRNA00153-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KIZ (kizuna centrosomal protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C20orf19; centrosomal protein kizuna; HT013; Kizuna; NCRNA00153; PLK1S1; polo-like kinase 1 substrate 1; RP69
Description (eCommerce)
KIZUNA has been identified as a centrosomal substrate of the polo-like kinase 1 (PLK1) which plays an essential role in bipolar spindle-pole formation. KIZUNA has been demonstrated to be critical for proper and stable centrosome structure that ensures spindle bipolarity.
Gene ID
55857
Gene Name (eCommerce)
kizuna centrosomal protein
Gene Name (Vector)
kizuna centrosomal protein
Gene Symbol
KIZ
HGNC ID
HGNC:15865
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2022
ORF Size (bp)
2022 bp
Protein Name (eCommerce)
Centrosomal protein kizuna
RefSeq ID
NM_018474
RefSeq Synonyms
NM_018474, NM_001276389, NM_001163023, NM_001163022, BC113370, BC105093, BC045826,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,PLK1 Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
KIZUNA has been identified as a centrosomal substrate of the polo-like kinase 1 (PLK1) which plays an essential role in bipolar spindle-pole formation. KIZUNA has been demonstrated to be critical for proper and stable centrosome structure that ensures spindle bipolarity.
UniGene ID
Hs.187635
UniProt ID (eCommerce)
Q2M2Z5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.