human MYO7A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MYO7A.
shADV-216223
Ad-h-MYO7A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MYO7A (myosin VIIA). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DFNA11; DFNB2; MYOVIIA; MYU7A; NSRD2; USH1B
Description (Vector)
MYO7A is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. MYO7A encodes an unconventional myosin with a very short tail. Defects in this gene are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.
Gene ID
4647
Gene Name (Vector)
myosin VIIA
Gene Symbol
MYO7A
HGNC ID
HGNC:7606
ORF Size (aa)
6528
ORF Size (bp)
6528 bp
RefSeq ID
NM_000260
RefSeq Synonyms
NM_001127180, NM_001127179, NM_000260, BC172349,
Species
human
UniGene ID
Hs.370421
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.