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human MYLK3 shRNA silencing Adenovirus

Name 
Ad-h-MYLK3-shRNA
Cat No 
shADV-216195
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human MYLK3.

shADV-216195
Ad-h-MYLK3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MYLK3 (myosin light chain kinase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
caMLCK; MLCK; MLCK2
Description (Vector)
Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 (PubMed 18202317)).(supplied by OMIM, Jul 2008)
Gene ID
91807
Gene Name (Vector)
myosin light chain kinase 3
Gene Symbol
MYLK3
HGNC ID
HGNC:29826
ORF Size (aa)
2388
ORF Size (bp)
2388 bp
RefSeq ID
NM_182493
RefSeq Synonyms
NM_182493, NM_001308301, BC109097,
Species
human
UniGene ID
Hs.130465

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.