human MUTYH shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MUTYH.
shADV-216092
Ad-h-MUTYH-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MUTYH (mutY DNA glycosylase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MYH
Description (Vector)
MUTYH encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
4595
Gene Name (Vector)
mutY DNA glycosylase
Gene Symbol
MUTYH
HGNC ID
HGNC:7527
ORF Size (aa)
1608
ORF Size (bp)
1608 bp
RefSeq ID
NM_012222
RefSeq Synonyms
NM_012222, NM_001293196, NM_001293195, NM_001293192, NM_001293191, NM_001293190, NM_001128425, NM_001048174, NM_001048173, NM_001048172, NM_001048171, BC003178,
Species
human
UniGene ID
Hs.271353
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.