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human MTRF1L shRNA silencing Adenovirus

Name 
Ad-h-MTRF1L-shRNA
Cat No 
shADV-216050
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human MTRF1L.

shADV-216050
Ad-h-MTRF1L-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MTRF1L (mitochondrial translational release factor 1 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HMRF1L; MRF1L; mtRF1a
Description (Vector)
Mitochondrial DNA encodes 13 proteins that play essential roles in the respiratory chain, while all proteins involved in mitochondrial translation are encoded by nuclear genes that are imported from the cytoplasm. MTRF1L is a nuclear-encoded protein that functions as a releasing factor that recognizes termination codons and releases mitochondrial ribosomes from the synthesized protein (summary by Nozaki et al., 2008 (PubMed 18429816)).(supplied by OMIM, Nov 2010)
Gene ID
54516
Gene Name (Vector)
mitochondrial translational release factor 1 like
Gene Symbol
MTRF1L
HGNC ID
HGNC:21051
ORF Size (aa)
816
RefSeq ID
NM_019041
RefSeq Synonyms
NM_019041, NM_001301872, NM_001301871, NM_001301870, NM_001301047, NM_001114184, BC105973, BC014428, BC011873,
Species
human
UniGene ID
Hs.304818

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.