human MTMR2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MTMR2.
shADV-216016
Ad-h-MTMR2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MTMR2 (myotubularin related protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMT4B; CMT4B1; myotubularin-related protein 2; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; phosphatidylinositol-3-phosphatase; phosphatidylinositol-3-phosphate phosphatase; phosphoinositide-3-phosphatase
Description (eCommerce)
Myotubularin-related protein 2 (MTMR2) is a member of the myotubularin family of phosphoinositide lipid phosphatases. MTMR possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in the MTMR2 are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy [taken from NCBI Entrez Gene (Gene ID: 8898)].
Description (Vector)
MTMR2 is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.
Gene ID
8898
Gene Name (eCommerce)
myotubularin related protein 2
Gene Name (Vector)
myotubularin related protein 2
Gene Symbol
MTMR2
HGNC ID
HGNC:7450
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1932
ORF Size (bp)
1932 bp
Protein Name (eCommerce)
Myotubularin-related protein 2
RefSeq ID
NM_016156
RefSeq Synonyms
NM_201281, NM_201278, NM_016156, NM_001243571, BC052990,
Research Areas
Kinase/Phosphatase,Metabolism/Metabolic Process,Neurobiology,Neurodegeneration,Neurodevelopment
Research Areas (Faceted)
cell_biology,developmental_biology,metabolism,neurobiology,signal_transduction
Species
human
Target Sentence
Myotubularin-related protein 2 (MTMR2) is a member of the myotubularin family of phosphoinositide lipid phosphatases. MTMR possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in the MTMR2 are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy [taken from NCBI Entrez Gene (Gene ID: 8898)].
UniGene ID
Hs.181326
UniProt ID (eCommerce)
Q13614
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.