human MTIF2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MTIF2.
shADV-216001
Ad-h-MTIF2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MTIF2 (mitochondrial translational initiation factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
4528
Gene Name (Vector)
mitochondrial translational initiation factor 2
Gene Symbol
MTIF2
HGNC ID
HGNC:7441
ORF Size (aa)
2181
ORF Size (bp)
2181 bp
RefSeq ID
NM_002453
RefSeq Synonyms
NM_002453, NM_001321005, NM_001321004, NM_001321003, NM_001321002, NM_001321001, NM_001005369, BC141420,
Species
human
UniGene ID
Hs.149894
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.