human MSLN shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MSLN.
shADV-215924
Ad-h-MSLN-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MSLN (mesothelin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MPF; SMRP
Description (Vector)
MSLN encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.
Gene ID
10232
Gene Name (Vector)
mesothelin
Gene Symbol
MSLN
HGNC ID
HGNC:7371
ORF Size (aa)
1866
ORF Size (bp)
1866 bp
RefSeq ID
NM_013404
RefSeq Synonyms
NM_013404, NM_005823, NM_001177355, BC009272, BC003512,
Species
human
UniGene ID
Hs.408488
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.