human MRPS33 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MRPS33.
shADV-215868
Ad-h-MRPS33-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MRPS33 (mitochondrial ribosomal protein S33). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CGI-139; MRP-S33; PTD003; S33mt
Description (Vector)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C. elegans. Splice variants that differ in the 5' UTR have been found for this gene; all variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q, 4p, 4q, and 20q
Gene ID
51650
Gene Name (Vector)
mitochondrial ribosomal protein S33
Gene Symbol
MRPS33
HGNC ID
HGNC:16634
ORF Size (aa)
321
RefSeq ID
NM_016071
RefSeq Synonyms
NM_053035, NM_016071, BC015462,
Species
human
UniGene ID
Hs.416207
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.