human MRPS18C shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MRPS18C.
shADV-215855
Ad-h-MRPS18C-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MRPS18C (mitochondrial ribosomal protein S18C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CGI-134; MRP-S18-1; MRP-S18-c; MRPS18-1; mrps18-c; S18mt-c
Description (Vector)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q.
Gene ID
51023
Gene Name (Vector)
mitochondrial ribosomal protein S18C
Gene Symbol
MRPS18C
HGNC ID
HGNC:16633
ORF Size (aa)
429
RefSeq ID
NM_016067
RefSeq Synonyms
NM_016067, NM_001297770, NM_001297769, NM_001297767, BC005186,
Species
human
UniGene ID
Hs.436161
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.