human MRPL47 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MRPL47.
shADV-215831
Ad-h-MRPL47-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MRPL47 (mitochondrial ribosomal protein L47). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CGI-204; L47mt; MRP-L47; NCM1
Description (Vector)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified.
Gene ID
57129
Gene Name (Vector)
mitochondrial ribosomal protein L47
Gene Symbol
MRPL47
HGNC ID
HGNC:16652
ORF Size (aa)
693
RefSeq ID
NM_020409
RefSeq Synonyms
NM_177988, NM_020409, BC032522, BC021575,
Species
human
UniGene ID
Hs.283734
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.