human MMP3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MMP3.
shADV-215596
Ad-h-MMP3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MMP3 (matrix metallopeptidase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CHDS6; MMP-3; SL-1; STMY; STMY1; STR1
Description (Vector)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Gene ID
4314
Gene Name (Vector)
matrix metallopeptidase 3
Gene Symbol
MMP3
HGNC ID
HGNC:7173
ORF Size (aa)
1434
ORF Size (bp)
1434 bp
RefSeq ID
NM_002422
RefSeq Synonyms
NM_002422, BC107491, BC107490, BC105954, BC074869, BC074815, BC069716, BC069676,
Species
human
UniGene ID
Hs.375129
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.