human MMP19 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MMP19.
shADV-215584
Ad-h-MMP19-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MMP19 (matrix metallopeptidase 19). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CODA; MMP18; RASI-1
Description (Vector)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This protein is expressed in human epidermis and it has a role in cellular proliferation as well as migration and adhesion to type I collagen. Multiple transcript variants encoding distict isoforms have been identified for this gene.
Gene ID
4327
Gene Name (Vector)
matrix metallopeptidase 19
Gene Symbol
MMP19
HGNC ID
HGNC:7165
ORF Size (aa)
1527
ORF Size (bp)
1527 bp
RefSeq ID
NM_002429
RefSeq Synonyms
NM_002429, NM_001272101, BC050368,
Species
human
UniGene ID
Hs.591033
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.