human MMP17 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MMP17.
shADV-215582
Ad-h-MMP17-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MMP17 (matrix metallopeptidase 17). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MMP-17; MT4-MMP; MT4MMP; MTMMP4
Description (Vector)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
Gene ID
4326
Gene Name (Vector)
matrix metallopeptidase 17
Gene Symbol
MMP17
HGNC ID
HGNC:7163
ORF Size (aa)
1821
ORF Size (bp)
1821 bp
RefSeq ID
NM_016155
RefSeq Synonyms
NM_016155, BC045610, BC040507,
Species
human
UniGene ID
Hs.709245
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.