human MITF shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MITF.
shADV-215490
Ad-h-MITF-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MITF (melanogenesis associated transcription factor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHe32; CMM8; MI; WS2; WS2A
Description (Vector)
MITF encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
4286
Gene Name (Vector)
melanogenesis associated transcription factor
Gene Symbol
MITF
HGNC ID
HGNC:7105
ORF Size (aa)
1260
ORF Size (bp)
1260 bp
RefSeq ID
NM_000248
RefSeq Synonyms
NM_198178, NM_198177, NM_198159, NM_198158, NM_006722, NM_001184968, NM_001184967, NM_000248, BC065243, BC026961, BC012503,
Species
human
UniGene ID
Hs.618266
Recently Viewed Products
AAV-h-PCP2
Cat No: AAV-218402
Ad-h-RABGAP1-shRNA
Cat No: shADV-220606
Ad-h-SMPDL3A-shRNA
Cat No: shADV-223770
AAV-h-NOS3-shRNA
Cat No: shAAV-216906
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.