human MARK4 shRNA silencing Adenovirus

Name 
Ad-h-MARK4-shRNA
Cat No 
shADV-215039
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human MARK4.

shADV-215039
Ad-h-MARK4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MARK4 (microtubule affinity regulating kinase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MARK4L; MARK4S; MARKL1; MARKL1L; PAR-1D
Description (Vector)
MARK4 encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
57787
Gene Name (Vector)
microtubule affinity regulating kinase 4
Gene Symbol
MARK4
HGNC ID
HGNC:13538
ORF Size (aa)
2067
ORF Size (bp)
2067 bp
RefSeq ID
NM_031417
RefSeq Synonyms
NM_031417, NM_001199867, BC166620, BC071948, BC009049,
Species
human
UniGene ID
Hs.34314

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.