human MARCKSL1 shRNA silencing Adenovirus

Name 
Ad-h-MARCKSL1-shRNA
Cat No 
shADV-215032
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human MARCKSL1.

shADV-215032
Ad-h-MARCKSL1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MARCKSL1 (MARCKS like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
F52; MACMARCKS; mac-MARCKS; macrophage myristoylated alanine-rich C kinase substrate; MARCKS-like protein 1; MARCKS-related protein; MLP; MLP1; MRP
Description (eCommerce)
MARCKS-like 1 (macrophage myristoylated alanine-rich C kinase substrate) has been identified in retinal membrane fractions as a myristoylated protein that may be involved in regulating cell proliferation.
Description (Vector)
MARCKSL1 encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.
Gene ID
65108
Gene Name (eCommerce)
MARCKS like 1
Gene Name (Vector)
MARCKS like 1
Gene Symbol
MARCKSL1
HGNC ID
HGNC:7142
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
588
Protein Name (eCommerce)
MARCKS-related protein
RefSeq ID
NM_023009
RefSeq Synonyms
NM_023009, BC066915, BC007904,
Research Areas
Immunology,Transport
Research Areas (Faceted)
immunology,cell_biology
Species
human
Target Sentence
MARCKS-like 1 (macrophage myristoylated alanine-rich C kinase substrate) has been identified in retinal membrane fractions as a myristoylated protein that may be involved in regulating cell proliferation.
UniGene ID
Hs.707012
UniProt ID (eCommerce)
P49006

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.