human MARCH2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MARCH2.
shADV-215015
Ad-h-MARCH2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MARCH2 (membrane associated ring-CH-type finger 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HSPC240; MARCH-II; RNF172
Description (Vector)
MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 (PubMed 14722266); Nakamura et al., 2005 (PubMed 15689499)).(supplied by OMIM, Mar 2010)
Gene ID
51257
Gene Name (Vector)
membrane associated ring-CH-type finger 2
Gene Symbol
2-Mar
HGNC ID
HGNC:28038
ORF Size (aa)
741
RefSeq ID
NM_016496
RefSeq Synonyms
NM_016496, NM_001005416, NM_001005415, BC111388, BC032624,
Species
human
UniGene ID
Hs.631861
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.