human MAP3K11 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MAP3K11.
shADV-214924
Ad-h-MAP3K11-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MAP3K11 (mitogen-activated protein kinase kinase kinase 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MEKK11; MLK-3; MLK3; PTK1; SPRK
Description (Vector)
MAP3K11 is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
Gene ID
4296
Gene Name (Vector)
mitogen-activated protein kinase kinase kinase 11
Gene Symbol
MAP3K11
HGNC ID
HGNC:6850
ORF Size (aa)
2544
ORF Size (bp)
2544 bp
RefSeq ID
NM_002419
RefSeq Synonyms
NM_002419, BC064543, BC011263,
Species
human
UniGene ID
Hs.502872
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.