human MAFK shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MAFK.
shADV-214798
Ad-h-MAFK-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MAFK (MAF bZIP transcription factor K). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NFE2U; P18
Description (Vector)
The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.(supplied by OMIM, Nov 2008)
Gene ID
7975
Gene Name (Vector)
MAF bZIP transcription factor K
Gene Symbol
MAFK
HGNC ID
HGNC:6782
ORF Size (aa)
471
RefSeq ID
NM_002360
RefSeq Synonyms
NM_002360, BC148265,
Species
human
UniGene ID
Hs.520612
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.