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human LPCAT4 shRNA silencing Adenovirus

Name 
Ad-h-LPCAT4-shRNA
Cat No 
shADV-214453
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human LPCAT4.

shADV-214453
Ad-h-LPCAT4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human LPCAT4 (lysophosphatidylcholine acyltransferase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1-acylglycerol-3-phosphate O-acyltransferase 7; 1-acylglycerol-3-phosphate O-acyltransferase 7 (lysophosphatidic acid acyltransferase, eta); 1-acylglycerophosphocholine O-acyltransferase; 1-acylglycerophosphoserine O-acyltransferase; 1-AGP acyltransferase 7; 1-AGPAT 7; 1-alkenylglycerophosphoethanolamine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; acyl-CoA:lysophosphatidylethanolamine acyltransferase 2; acyltransferase-like 3; AGPAT7; AYTL3; LPAAT-eta; LPEAT2; Lysophosphatidylcholine acyltransferase 4; lysophosphatidylethanolamine acyltransferase 2; lysophospholipid acyltransferase LPCAT4; plasmalogen synthase; PLSC domain containing protein
Description (eCommerce)
Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as LPCAT4, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]) [taken from NCBI Entrez Gene (Gene ID: 254531)].
Description (Vector)
Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as AGPAT7, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 (PubMed 16243729)).(supplied by OMIM, May 2008)
Gene ID
254531
Gene Name (eCommerce)
lysophosphatidylcholine acyltransferase 4
Gene Name (Vector)
lysophosphatidylcholine acyltransferase 4
Gene Symbol
LPCAT4
HGNC ID
HGNC:30059
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1575
ORF Size (bp)
1575 bp
Protein Name (eCommerce)
Lysophospholipid acyltransferase LPCAT4
RefSeq ID
NM_153613
RefSeq Synonyms
NM_153613, BC092463,
Research Areas
Acyltransferase,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Members of the 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) family, such as LPCAT4, catalyze the conversion of lysophosphatidic acid (LPA) to phosphatidic acid (PA), a precursor in the biosynthesis of all glycerolipids. Both LPA and PA are involved in signal transduction (Ye et al., 2005 [PubMed 16243729]) [taken from NCBI Entrez Gene (Gene ID: 254531)].
UniGene ID
Hs.352614
UniProt ID (eCommerce)
Q643R3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.