human AFF3 shRNA silencing Adenovirus

Name 
Ad-h-AFF3-shRNA
Cat No 
shADV-214339
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human AFF3.

shADV-214339
Ad-h-AFF3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AFF3 (AF4/FMR2 family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
LAF4; MLLT2-like
Description (Vector)
AFF3 encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Gene ID
3899
Gene Name (Vector)
AF4/FMR2 family member 3
Gene Symbol
AFF3
HGNC ID
HGNC:6473
ORF Size (aa)
3681
ORF Size (bp)
3681 bp
RefSeq ID
NM_002285
RefSeq Synonyms
NM_002285, NM_001025108, BC144266, BC136579,
Species
human
UniGene ID
Hs.444414

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.