human RAB6A shRNA silencing Adenovirus

Name 
Ad-h-RAB6A-shRNA
Cat No 
shADV-214123
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RAB6A.

shADV-214123
Ad-h-RAB6A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RAB6A (RAB6A, member RAS oncogene family). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
RAB6
Description (Vector)
RAB6A encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
5870
Gene Name (Vector)
RAB6A, member RAS oncogene family
Gene Symbol
RAB6A
HGNC ID
HGNC:9786
ORF Size (aa)
627
RefSeq ID
NM_002869
RefSeq Synonyms
NM_198896, NM_002869, NM_001243719, NM_001243718, BC096818, BC068486, BC003617,
Species
human
UniGene ID
Hs.535586

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.