human SNAP25 shRNA silencing Adenovirus

Name 
Ad-h-SNAP25-shRNA
Cat No 
shADV-214114
Availability
Immediate
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SNAP25.

shADV-214114
Ad-h-SNAP25-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SNAP25 (synaptosome associated protein 25). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bA416N4.2; CMS18; dJ1068F16.2; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SUP
Description (Vector)
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Gene ID
6616
Gene Name (Vector)
synaptosome associated protein 25
Gene Symbol
SNAP25
HGNC ID
HGNC:11132
ORF Size (aa)
621
RefSeq ID
NM_003081
RefSeq Synonyms
NM_130811, NM_003081, NM_001322910, NM_001322909, NM_001322908, NM_001322907, NM_001322906, NM_001322905, NM_001322904, NM_001322903, NM_001322902, BC010647,
Species
human
UniGene ID
Hs.167317

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.