human LMBR1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human LMBR1.
shADV-214011
Ad-h-LMBR1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human LMBR1 (limb development membrane protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACHP; C7orf2; DIF14; LSS; PPD2; THYP; TPT; ZRS
Description (Vector)
LMBR1 encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.
Gene ID
64327
Gene Name (Vector)
limb development membrane protein 1
Gene Symbol
LMBR1
HGNC ID
HGNC:13243
ORF Size (aa)
1473
ORF Size (bp)
1473 bp
RefSeq ID
NM_022458
RefSeq Synonyms
NM_022458, BC017663,
Species
human
UniGene ID
Hs.209989
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.