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human KRT6B shRNA silencing Adenovirus

Name 
Ad-h-KRT6B-shRNA
Cat No 
shADV-213438
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human KRT6B.

shADV-213438
Ad-h-KRT6B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KRT6B (keratin 6B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CK-6B; CK6B; K6B; KRTL1; PC2; PC4
Description (Vector)
KRT6B is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Gene ID
3854
Gene Name (Vector)
keratin 6B
Gene Symbol
KRT6B
HGNC ID
HGNC:6444
ORF Size (aa)
1695
ORF Size (bp)
1695 bp
RefSeq ID
NM_005555
RefSeq Synonyms
NM_005555, BC034535,
Species
human
UniGene ID
Hs.709235

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.