human KRT16 shRNA silencing Adenovirus

Name
Ad-h-KRT16-shRNA

Cat No
shADV-213381

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human KRT16.

shADV-213381

Ad-h-KRT16-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human KRT16 (keratin 16). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CK-16; CK16; Cytokeratin-16; FNEPPK; K16; K1CP; KRT16A; Keratin-16; NEPPK; PC1; cytokeratin 16; focal non-epidermolytic palmoplantar keratoderma; keratin 16, type I; keratin, type I cytoskeletal 16

Description (Vector)

KRT16 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

Gene ID

3868

Gene Name (eCommerce)

keratin 16

Gene Name (Vector)

keratin 16

Gene Symbol

KRT16

HGNC ID

HGNC:6423

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1422

ORF Size (bp)

1422 bp

Protein Name (eCommerce)

Keratin, type I cytoskeletal 16

RefSeq ID

NM_005557

RefSeq Synonyms

NM_005557, BC039169,

Research Areas

Cytoskeleton

Research Areas (Faceted)

cell_biology

Species

human

UniGene ID

Hs.655160

UniProt ID (eCommerce)

P08779

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.